@article { author = {Alavinia, Seyed Jalil and Mirzargar, Seyed Saeed and Rahmati-Holasoo, Homan and mousavi, Hosseinali}, title = {In vitro Investigation of Short-Term Antiparasitic Effect of Tannic Acid on Ichthyophthirius multifiliis Theronts}, journal = {Journal of Veterinary Research}, volume = {74}, number = {2}, pages = {219-227}, year = {2019}, publisher = {The University of Tehran Press}, issn = {2008-2525}, eissn = {2251-6190}, doi = {10.22059/jvr.2019.244686.2720}, abstract = {BACKGROUND: Ichthyophthiriasis induced by a freshwater teleost pathogen “Ichthyophthirius multifiliis” is one of the most important parasitic diseases with substantial economic losses to the aquaculture industry. Although malachite green, copper sulphate, formalin, and chloramine-T have been used to treat ichthyophthiriasis, there are  no chemicals that can be used safely and effectively to control this parasitic disease. As a result, application of natural, safe and strong components to prevent ichthyophthiriasis is of great importance. Objective: The aim of the present research is to determine the short-term effectiveness of tannic acid (TA) on the parasite theronts of I. multifiliis. Methods: In this study, TA as a main phenolic acid at different concentrations (0.0-7.0 mg/L) was applied to determine its acute toxicity against I. multifiliis theronts in various exposure times (1-3 h). The results were also statistically compared to the findings obtained from the control treatment and the positive control sample (15mg/L  formalin). Results: There was a significant and direct correlation between TA concentration and exposure time in order to enhance the mortality rate of I. multifiliis theronts. An increase in levels of TA and exposure time in the studied ranges can significantly intensify the mortality number (P<0.05). The used natural phenolic constituent similar to 15 mg/L formalin led to a significant reduction in number of these theronts (> 80%) at 60 min. Conclusions: Use of a standard phenolic agent such as TA at higher concentration and longer exposure time can potentially decrease the number of I. multifiliis theronts and control ichthyophthiriasis.}, keywords = {phenolic compounds,Anti,Mortality rate,Antiparasitic efficacy,Acute toxicity,White spot disease}, title_fa = {بررسی اثر ضد انگلی کوتاه مدت اسید تانیک بر ترونتهای ایکتیوفتیریوس مولتی فیلیس (Ichthyophthirius multifiliis) در شرایط آزمایشگاهی}, abstract_fa = {}, keywords_fa = {ترکیبات فنولی,نرخ کشندگی,کارایی ضد انگلی,بیماری دانه های سفید,ایک}, url = {https://jvr.ut.ac.ir/article_71649.html}, eprint = {https://jvr.ut.ac.ir/article_71649_facd17f04821bbc1e2f5f401d007aed0.pdf} }