University of Tehran Press Journal of Veterinary Research 2008-2525 63 1 2008 03 20 EXPERIMENTAL STUDY ON THE RELATIONSHIP BETWEEN NUTRITIONAL HYPOPHOSPHATEMIA AND HEMOGLOBINURIA IN THE LAMBS EXPERIMENTAL STUDY ON THE RELATIONSHIP BETWEEN NUTRITIONAL HYPOPHOSPHATEMIA AND HEMOGLOBINURIA IN THE LAMBS 33 39 23915 FA Naser Alidadi 0000-0002-1072-1851 Mohsen Ghahhar Parvaneh Khazraeenia Zohreh Khaki Ali Reza Bahonar Saeed Sattari Parastoo Yousefi Journal Article This study was designed to induce nutritional hypophosphatemia to investigate the possibility of intervascular hemolysis in the control (7 lambs) and test (8 lambs) groups. Phosphorus of the ration for the test and control groups was formulated as 0.063 % and 0.34% of dry matter, respectively. The jugular vein blood samples were weekly taken for inorganic phosphorus, alkaline phosphatase, billirubin, hematocrit and Heinz body examination. The indepentent t-test and repeated measures )analysis of variance) methods applied for the statistical analyses. Significant hypophosphatemia (p<0.01) and increase in the alkaline phosphatase activity (p<0.001) observed in the test lambs. Hienz bodies in the red blood cells and higly significant decrease of the hematocrit (p< 0/0005) appeared in both groups. Although, visible hemoglobinuria was not observed. The results cleares up potential sensitivity of sheep to nutritional hemolysis. This study was designed to induce nutritional hypophosphatemia to investigate the possibility of intervascular hemolysis in the control (7 lambs) and test (8 lambs) groups. Phosphorus of the ration for the test and control groups was formulated as 0.063 % and 0.34% of dry matter, respectively. The jugular vein blood samples were weekly taken for inorganic phosphorus, alkaline phosphatase, billirubin, hematocrit and Heinz body examination. The indepentent t-test and repeated measures )analysis of variance) methods applied for the statistical analyses. Significant hypophosphatemia (p<0.01) and increase in the alkaline phosphatase activity (p<0.001) observed in the test lambs. Hienz bodies in the red blood cells and higly significant decrease of the hematocrit (p< 0/0005) appeared in both groups. Although, visible hemoglobinuria was not observed. The results cleares up potential sensitivity of sheep to nutritional hemolysis. https://jvr.ut.ac.ir/article_23915_f5a3c9c5f11be9cf40a145775cfddc60.pdf