دانشگاه تهران مجله تحقیقات دامپزشکی (Journal of Veterinary Research) 2008-2525 62 1 2007 03 21 CHOLANGIOCARCINOMA IN A BROILER CHICKEN گزارش یک مورد کلانژیوکارسینوما در یک قطعه جوجه گوشتی 63 64 24028 FA سید مصطفی پیغمبری گروه علوم درمانگاهی، دانشکده دامپزشکی دانشگاه تهران امید دزفولیان بخش آسیب شناسی، آموزشکده دامپزشکی دانشگاه لرستان مهدی رزازیان کلینیک خصوصی طیور، خیابان توحید، خیابان فرصت شیرازی، شماره 217 Journal Article 1970 01 01 Twenty carcasses from a small flock of 5000 four-weeks old broiler chickens were submitted to a poultry disease diagnostic clinic in Tehran. At necropsy, 19 carcasses showed the typical lesions of colibacillosis such as pericarditis, prihepatitis and airsaculitis. One case did not show any gross lesion of colibacillosis or chronic respiratory disease (CRD) but the liver had an abnormal size containing a cystic part at the base of right lobe filled with a whitish fluid. In bacteriological culture, proteus was isolated from liver. Histopathological examination revealed multicentric bile duct hyperplasia and cholangiocarcinoma in the liver. Neoplastic cells effaced hepatocellular architecture. Histological examination of the neoplastic areas in the liver revealed cholangiocarcinoma (bile duct carcinoma). This appears to be the first reported case of cholangiocarcinoma in birds in Iran. Twenty carcasses from a small flock of 5000 four-weeks old broiler chickens were submitted to a poultry disease diagnostic clinic in Tehran. At necropsy, 19 carcasses showed the typical lesions of colibacillosis such as pericarditis, prihepatitis and airsaculitis. One case did not show any gross lesion of colibacillosis or chronic respiratory disease (CRD) but the liver had an abnormal size containing a cystic part at the base of right lobe filled with a whitish fluid. In bacteriological culture, proteus was isolated from liver. Histopathological examination revealed multicentric bile duct hyperplasia and cholangiocarcinoma in the liver. Neoplastic cells effaced hepatocellular architecture. Histological examination of the neoplastic areas in the liver revealed cholangiocarcinoma (bile duct carcinoma). This appears to be the first reported case of cholangiocarcinoma in birds in Iran. https://jvr.ut.ac.ir/article_24028_a1afe99b3581416643326847b707f686.pdf