University of Tehran Press Journal of Veterinary Research 2008-2525 71 2 2016 06 21 Comparison of the effects extract of rosemary, thyme, propolis, antibiotic and probiotic on the immune system and blood parameters of broilers chickens challenged with Salmonella Enteritidis Comparison of the effects extract of rosemary, thyme, propolis, antibiotic and probiotic on the immune system and blood parameters of broilers chickens challenged with Salmonella Enteritidis 245 253 57923 10.22059/jvr.2016.57923 FA Masoud Taher Department of Poultry Sciences, Faculty of Agriculture, Tarbiat Modares University, Tehran, Iran Shaban Rahimi Department of Poultry Sciences, Faculty of Agriculture, Tarbiat Modares University, Tehran, Iran Mohammad Amir Karimi Torshizi Department of Poultry Sciences, Faculty of Agriculture, Tarbiat Modares University, Tehran, Iran Abbas Ashouri Department of Poultry Sciences, Faculty of Agriculture, Tarbiat Modares University, Tehran, Iran Sakineh Babaei Department of Poultry Sciences, Faculty of Agriculture, Tarbiat Modares University, Tehran, Iran Journal Article 2016 03 05 <strong>BACKGROUND:</strong> <em>Salmonella</em> Enteritidis in poultry is one of the main causes of illness that can be controlled effectively by some plant compounds, antibiotics and probiotics. <strong>OBJECTIVES:</strong> This study compares the effect of rosemary, thyme, propolis, antibiotic and probiotic on the immune system and blood parameters of broilers challenged with Salmonella Enteritidis.  <strong>Methods:</strong> Four hundred and twenty 1-day- old male broiler chicks Cobb strain were divided into seven groups: including rosemary ethanol extract, ethanol extract of propolis, ethanol extract of thyme, and probiotics, virginiamycin (10%) and positive and negative controls, and were reared for 6 weeks. At the end of experiment chickens were sampled and slaughtered. <strong>RESULTS:</strong> The results showed that plant extracts with probiotics can improve the immune system, reduce serum lipids, reduce harmful bacteria such as <em>Salmonella</em> and <em>E.coli</em> and increase the beneficial bacteria such as lactic acid bacteria. <strong>CONCLUSIONS:</strong> This study showed that the herbal extracts and probiotics can be used as an alternative to antibiotics in broiler diets. <strong>BACKGROUND:</strong> <em>Salmonella</em> Enteritidis in poultry is one of the main causes of illness that can be controlled effectively by some plant compounds, antibiotics and probiotics. <strong>OBJECTIVES:</strong> This study compares the effect of rosemary, thyme, propolis, antibiotic and probiotic on the immune system and blood parameters of broilers challenged with Salmonella Enteritidis.  <strong>Methods:</strong> Four hundred and twenty 1-day- old male broiler chicks Cobb strain were divided into seven groups: including rosemary ethanol extract, ethanol extract of propolis, ethanol extract of thyme, and probiotics, virginiamycin (10%) and positive and negative controls, and were reared for 6 weeks. At the end of experiment chickens were sampled and slaughtered. <strong>RESULTS:</strong> The results showed that plant extracts with probiotics can improve the immune system, reduce serum lipids, reduce harmful bacteria such as <em>Salmonella</em> and <em>E.coli</em> and increase the beneficial bacteria such as lactic acid bacteria. <strong>CONCLUSIONS:</strong> This study showed that the herbal extracts and probiotics can be used as an alternative to antibiotics in broiler diets. https://jvr.ut.ac.ir/article_57923_2a1be4a130060ed6b9460bcb467d3135.pdf