Changes in clinical signs after treatment in calves with experimental colisepticemia with Escherichia coli

Authors

1 Department of Internal Medicine, Faculty of Veterinary Medicine University of Tehran, Tehran, Iran

2 Associated professor of Department of Clinical Sciences, Faculty of Veterinary Medicine University of Tehran, Tehran-Iran

3 Department of Dignostic Microbiology, Iran Veterinary Organization, Central Veterinary Laboratory, Tehran, Iran

4 Department of Surgery and Radiology, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran

5 Department of Microbiology, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran

6 Research & Production Complex Institute of Pasteur, Tehran, Iran

7 Graduated from the Faculty of Veterinary Medicine University of Tehran, Tehran, Iran

Abstract

Background: Colisepticemia is an acute fatal disease in farm animal neonates. Clinical finding of septicemia is non-specific and cannot be differentiate from signs of non-infectious disease or disease with local infection such as diarrhea. Object: Evaluation of clinical signs variations in calves with experimental septicemia with Escherichia coli O111:H8. Methods: Colisepticemia were experimentally induced in ten Holstein bull calves after an adaptation period. Vital signs and 7 clinical criteria were recorded from 24h before septicemia until 48h after that. Blood culture was performed and treatment was done based on antibiogram from 24h after challenge. Results: Changes of suckling reflex and shock were not significant. Changes of appetite, dehydration, behavior, standing ability, total score from 24h before the challenge to 24h after treatment were significant(P

Keywords

References

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