In order to evaluate of skin reactions to C. albicans antigens, a study was caned out during 12 months period. A total of 180 patients (95 cases of A topic dermatitis and 85 Asthmatic patients), from outpatient Clinics of Dermatology, Imam Khomeini Hospital and Tehran Allergy Clinic were selected. From these patients 62 (34.4%) were male and 118 (65.6%) were female. After preparation of the antigens, the skin prick test was performed for all the patients. The positive results were obtained in 53.3% of patients and 4.3% of healthy controls. In this study, the same positive results in a topic dermatitis and asthmatic patients were 52.6% and 54.1%, respectively. The most common positive responses age group, were 20-29 and >50 years old.
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