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Abstract

To evaluate the effects of intoxication with trichlorofon on serum biochemical parameters, an experiment was conducted with 60 Silver carp. Experimental fish were divided into 3 different groups:
control group (n = 12), intoxicated group with 0.25 ppm of trichlorofon (n = 24) and intoxicated group with 1 ppm of trichlorofon (n = 24). Blood samples were collected before the administration of trichlorofon for obtaining control values. Following the administration of trichlorofon, blood samples were collected 5 times at 0 , 12 , 24 , 36 and 48 hours post administration. Following the intoxication with 0.25 ppm of trichlorofon, there was no significant difference in any of the serum biochemical parameters. After the intoxication with 1 ppm of trichlorofon the concentration of inorganic phosphorus and the activites of AST, ALT and ALP significantly increased (P <0.05) However, the concentration of total protein, albumin, sodium and blood urea nitrogen significantly decreased (P < 0.05). Following the intoxication with 0.25 ppm and 1 ppm of trichlorofon , in different times of post intoxication. there was no significant difference in any of the biochemical parameters. No significant interaction was observed between dose and time of post intoxication with trichiorofon. This study showed that intoxication with trichlorofon can have profound effects on some serum biochemical parameters of Silver carp.

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