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Abstract

Objective: Comparison of intraocular pressure alternations measured
by Schiotz tonometry before and after induction of anesthezia by
ketamine and acepromazine in stray cats. The effects of factors like age, sex and iris color on intraocular pressure were also studied. Design: Uncontrolled clinical trial.
Animals: Hundred stray cats were used in the study.
Material and methods: Hundred stray cats were collected from different portions of Tehran by a special cage designed to do this. To improve the accuracy of data in each case measurement was
performed three times and it’s average was recorded as lOP in that
animal. Furthermore, because in many clinical examinations
especially when the animal suffer from pain due to glaucoma use of anesthesia is obligatory and to assess the effect of anesthesia on
lOP, all of the cats were anesthetized by ketamine hydrochloride
and acepromazine in traditional doses and lOPs were measured again in this situation.
Statistical analysis: In this study statistical analysis were performed by independent t test, paired t test, one way ANOVA and tookey as complementary test.
Results: In this study, the mean of lOP was 17.5 ± 0.46 mmHg. Furthermore, the results of this study showed that sex and color of
iris had no significant effect in lOP, but in respect to age based on
statistical ANOVA test, the difference was significant. Younger animals had higher values of lOP compared with older cats. Beside this, the results of this study showed that anesthesia with ketamine
and acepromazine in cats can lead to increase in IOP and X =
formula, as an index, can be used for lOP determination in situations that anesthesia performance is obligatory (x = corrected lOP value before anesthesia induction, y = acquired lOP value after
anesthesia).
Discussion: From the factors evaluated in this study, just age had a significant influence on lOP. Beside this for determination of glaucoma especially when use of ketamine and acepromazine are
obligatory and there is considerable pain in the patient and physical restraint is impossible, this could lead in increase of lOP in affected
animals. To evaluate lOP properly in this conditions use of correction
coefficients could be helpful.

Keywords