Prevalence of clinical and subclinical form of caprine mastitis, determination of different antibiotic resistant patterns along with the lactamase production exhibited by penicillin, amoxicillin, ampicillin, and cephalexin resistance strains isolated from cases of caprine mastitis were studied. The occurrence of subclinical and clinical mastitis was 26.8% and 2.4% respectively. A total of 55 isolates comprising coagulase positive Staphylococci (41.8%), coagulase negative Staphylococci (29%), Bacillus cereus (7.3%), E. cohi (7.3%), alfahemolytic Streptococcus (3.6%), Micrococcus (3.6%), Neisseria meningococcus (1.8%), Enterobacter (1.8%), Pseudomonas multiphilia (1.8%) and Proteus (1.8%) strains were identified. Antibiotic sensitivity testing showed that between 0% (alfahemolytic Streptococcus, Micrococcus, Neisseria meningococcus, Proteus) and 100% (E. coli, Pseudomonas multiphilia, Enterobacter) were resistant to one or more antibiotics. The capillary method was able to detect lactamase production in 93.1% of isolates while the acidometric detected only 65.5% of isolates.