Objective: To Study the effects of turpentine powder on the concentration of lipids and lipoproteins of rabbit (as an animal model for human studies).
Design: Experimental Study.
Animals: 30 healthy female rabbits.
Procedure: 30 healthy female rabbits were chosen and then randomly allocated into 6 groups of 5 rabbits each. Different percent ages of turpentine powder (10% and 100%) and oil compounds (vegetable oil, cholesterol and animal oil) were given to each group, separately. Blood serum lipid and lipoprotein levels were analyzed using routine laboratory methods. Statistical analysis: Analysis of variance and Duncan’s multiple range test.
Results: Treatment with 10% and 100% turpentine powder had significant decreasing effect on Serum triglyceride, cholesterol, total lipid, VLDL- cholesterol and LDL- cholesterol (P<0.05 ) Moreover, it significantly increased the Serum HDL- cholesterol (P<0.05). Treatment with 10% vegetable oil had a significant increasing effect on the serum triglyceride and VLDL-cholesterol (P<0.05). Following treatment with 10% animal oil, the concentration of HDL cholesterol showed a significant P<0.05) decrease while the concentration of cholesterol and LDL-cholesterol showed a significant increase (P<0.05).After treatment with 1% cholesterol, the concentration of serum HDL- cholesterol,
LDL-cholesterol, VLDL-cholesterol, triglyceride and total lipid significantly increased (P<0.05).
Conclusion: treatment with turpentine powder has significant effects on the levels of serum lipids and lipoproteins. J.Fac. Vet.Med. Univ. Tehran. 60,4:321- 326,2005.