Pathological study on central nervous system in Iranian cattle and buffaloes: A Provincial study


1 Department of Pathobiology, School of Veterinary Medicine, University of Shiraz , Shiraz-Iran

2 Razi Vaccine and Serum Research Institute, Karaj-Iran


BACKGROUND: Evaluation of clinical signs and pathological lesions could be very important for recognition of nervous system diseases in cattle and buffaloes. OBJECTIVES: This study was carried out to understand the nature of pathological conditions affecting brain of cattle and buffaloes in an abattoir study. METHODS: 46 samples out of 850 samples  (37 cattle, 9 buffaloes) which showed various macroscopic lesions were collected for detailed examination. The specimens were ginned processed through routine method for paraffin embedding section (5-7micron), stained by haematoxilyin and eosin method. RESULTS: Congestion and hemorrhage ( 8 cows, 9 buffaloes); pigmentation (4 cows); chromatolysis (4 cows, 2 buffaloes); gliosis (4 cows, 1 buffalo); vacuolization of the white matter (4 cows);  necrosis (6 cattles, 2 buffaloes); cerebellum edema (3 cows); perivascular cuffing (4 cows, 3 buffaloes); blood vessels hyperplasia (3 cows); coenurus cerebralis (3 cows); encephalitis (9 cattle, 1 buffalo); mineralization (5 cows); meningeal hemorrhage and congestion (10 cows, 9 buffaloes); meningeal edema (2 cows); meningitis (7 cows); cerebral congestion and hemorrhage (1cow, 5 buffaloes); degeneration of molecular layer (2 cows); degeneration of granular  layer  (3 cows) Purkinje cells degeneration (cows 4, 1 buffalo). CONCLUSIONS: Multiple lesions in the central nervous system have been observed in apparently healthy animals without clinical signs. Considering the importance of ruminants encephalopathy and comparing  these results can be a basis for further study.