Objective: To evaluate the efficacy of treatment in ovine babesiosis. Design : Experimental study. Animals: Thirty six sheep about 1-2 year -old. Procedure: Thirty six sheep , which were negative for any blood parasites, were selected. The animals were categorized into the splenectomized and unsplenectomized groups and each group into 3 subgroups: control, Diminazen and Imidocarb ones. Babesiosis was induced by intravenous injection of 5.2 x10o infected erythrocytes per animal.When body temperature and parasitemia raise, Diminazen (3.5 mg / kbw) and Imidocarb (1.2 mg / kbw) were administrated to each animal in the corresponding groups. Animals were kept up to day 9 post infection. After clinical manifestations, blood samples were daily collected from each animal and hematological parameters determined. Statistical analysis:t-student test. Discussion and Results : The results indicated that Diminazen is more effective than Imidocarb. Furthermore, clinical signs and parasites were recurred in the treated sheep with Imidocarb .
Khaki, Z., Rahbari, S., Nadealian, M. G., Alidadi, N., & Ashrafi Halan, J. (2006). Comparison of the Effect of Diminazen and Imidocarb in Experimentally Infected sh eep with Babesia ovis. Journal of Veterinary Research, 61(1), 43-46.
MLA
Zohreh Khaki; Sadegh Rahbari; Mohammad Gholi Nadealian; Naser Alidadi; Javad Ashrafi Halan. "Comparison of the Effect of Diminazen and Imidocarb in Experimentally Infected sh eep with Babesia ovis", Journal of Veterinary Research, 61, 1, 2006, 43-46.
HARVARD
Khaki, Z., Rahbari, S., Nadealian, M. G., Alidadi, N., Ashrafi Halan, J. (2006). 'Comparison of the Effect of Diminazen and Imidocarb in Experimentally Infected sh eep with Babesia ovis', Journal of Veterinary Research, 61(1), pp. 43-46.
VANCOUVER
Khaki, Z., Rahbari, S., Nadealian, M. G., Alidadi, N., Ashrafi Halan, J. Comparison of the Effect of Diminazen and Imidocarb in Experimentally Infected sh eep with Babesia ovis. Journal of Veterinary Research, 2006; 61(1): 43-46.